Table 1 –
Patient demographics, cardiac arrest characteristics by outcomes.
| Patient demographics/Cardiac arrest characteristics | All Patients (n = 34) | Favorable Outcome (n = 10) | Unfavorable Outcome (n = 24) | P-value |
|---|---|---|---|---|
|
| ||||
| Age (years), median’ (IQR) | 2.9 [1.5, 13.4] | 11.7 [2.7, 14.6] | 2.7 [0.7, 9.2] | 0.11 |
| Gender (male), N (%) | 24 (71) | 9 (90) | 15 (63) | 0.22 |
| Preexisting conditions | ||||
| None | 13 (38) | 6 (60) | 7 (29) | 0.09 |
| Premature infant | 10 (29) | 2 (20) | 8 (33) | 0.68 |
| Congenital heart disease | 6 (18) | 1 (10) | 5 (21) | 0.64 |
| Congenital malformation | 4 (12) | 0 (0) | 4 (17) | 0.30 |
| Cancer/BMT | 3 (9) | 1 (10) | 2 (8) | 1.00 |
| Respiratory disorder/CLD | 10 (29) | 1 (10) | 9 (38) | 0.22 |
| Renal insufficiency | 4 (12) | 1 (10) | 3 (13) | 1.00 |
| Neurological disorder | 5 (15) | 0 (0) | 5 (21) | 0.29 |
| Solid organ transplant | 1 (3) | 0 (0) | 1 (4) | 1.00 |
| Baseline PCPC | ||||
| PCPC 1 | 20 (59) | 8 (80) | 12 (50) | 0.47 |
| PCPC 2 | 4 (12) | 0 (0) | 4 (17) | |
| PCPC 3 | 6 (18) | 1 (10) | 5 (21) | |
| PCPC 4 | 4 (12) | 1 (10) | 3 (13) | |
| Arrest Etiology | 0.19 | |||
| Respiratory failure | 12 (35) | 3 (30) | 9 (38) | |
| Arrhythmia | 3 (9) | 3 (30) | 0 (0) | |
| Hypotension/shock/sepsis | 3 (9) | 1 (10) | 2 (8) | |
| Ingestion/toxic | 1 (3) | 0 (0) | 1 (4) | |
| Metabolic/electrolyte | 2 (6) | 1 (10) | 1 (4) | |
| Seizures | 1 (3) | 0 (0) | 1 (4) | |
| Drowning | 3 (9) | 0 (0) | 3 (13) | |
| Unknown | 9 (26) | 2 (20) | 7 (29) | |
| Out-of-hospital cardiac arrest | 22 (65) | 5 (50) | 17 (71) | 0.27 |
| CPR duration (min), (n = 27) | 12 [6,32] | 6 [5,10] | 28 [9, 36] | 0.01 |
| Number of Epi doses | 0.09 | |||
| 0–2 | 19 (56) | 9 (90) | 10 (42) | |
| 3–5 | 4 (12) | 0 (0) | 4 (17) | |
| >5 | 7 (21) | 1 (10) | 6 (25) | |
| Unknown | 4 (12) | 0 () | 4 (17) | |
| Initial Rhythm | ||||
| PEA/Asystole | 17 (50) | 3 (30) | 14 (58) | 0.06 |
| Bradycardia | 4 (12) | 2 (20) | 2 (8) | |
| V-tachycardia/fibrillation | 3 (9) | 3 (30) | 0 (0) | |
| Not documented/Unknown | 10 (29) | 2 (20) | 8 (33) | |
| Initial pH, median, (IQR) | 6.98 [6.81, 7.19] | 7.18 [7.05, 7.28] | 6.87 [6.75, 7.09] | 0.004 |
| Initial Lactate, median’ (IQR) | 7.3 [4.8, 11.3] | 6.0 [4.9, 7.3] | 8.0 [4.7, 12.7] | 0.14 |
| Temperature target | 0.07 | |||
| 33.0 °C | 4 (12) | 3 (30) | 1 (4) | |
| 36.0 °C | 30 (88) | 7 (70) | 23 (96) | |
| PCPC (hospital discharge) | <0.001 | |||
| PCPC 1 | 3 (9) | 3 (30) | 0 (0) | |
| PCPC 2 | 5 (15) | 5 (50) | 0 (0) | |
| PCPC 3 | 5 (15) | 1 (10) | 4 (17) | |
| PCPC 4 | 5 (15) | 1 (10) | 4 (17) | |
| PCPC 5 | 2 (6) | 0 (0) | 2 (8) | |
| PCPC 6 | 14 (41) | 0 (0) | 14 (58) | |
| PCPC Change (Discharge - Baseline) | <0.001 | |||
| 0 | 5 (15) | 5 (50) | 0 (0) | |
| 1 | 7 (21) | 5 (50) | 2 (8) | |
| 2 | 9 (27) | 0 (0) | 9 (38) | |
| 3 | 4 (12) | 0 (0) | 4 (17) | |
| 4 | 2 (6) | 0 (0) | 2 (8) | |
| 5 | 7 (21) | 0 (0) | 7 (29) | |