. Author manuscript; available in PMC: 2022 Jun 1.

Published in final edited form as: Hematol Oncol. 2021 Jun;39(Suppl 1):15–23. doi: 10.1002/hon.2857

Table 1.

Historical Classification of Histiocytic Disorders

Dendritic cell related

Langerhans cell histiocytosis

Juvenile xanthogranuloma/Erdheim-Chester disease

Macrophage related

Hemophagocytic syndromes

Primary hemophagocytic lymphohistiocytosis

Secondary hemophagocytic syndromes

Rosai-Dorfman disease

Malignant diseases

Monocyte-related leukemias

Extramedullary monocytic tumor (myeloid sarcoma)

Macrophage-related histiocytic sarcoma

Dendritic cell malignancy (malignant histiocytosis)

Adapted from ¹