Table 3.

Eight-Year Change in Subfoveal ChT in Eyes With Axial Elongation (in Tertiles) and Refractive Error Shift

8-y Change	8-y Change in ChT, µm	Statistical Difference*	P Value
Axial elongation, mm
• Tertile 1: <0.023 (n = 128 eyes)	Median = +30.4[IQR = +0.5 to +59.6]	Reference	Reference
• Tertile 2: 0.023–0.170 (n = 127 eyes)	Median = +7.0[IQR = −15.5 to 34.0]	Estimate = −22.4[95% CI = −35.8 to −8.9]	0.001‡
• Tertile 3: >0.170 (n = 130 eyes)	Median = −22.5[IQR = −63.6 to +11.8]	Estimate = −56.3[95% CI = −71.2 to −41.4]	<0.001‡
Refractive error shift †
• None (n = 263 eyes)	Median = +10.9[IQR = −12.3 to +41.6]	Reference	Reference
• Hyperopic (n = 18 eyes)	Median = +40.9[IQR = −2.8 to +71.2]	Estimate = 13.3[95% CI = −7.7 to +34.3]	0.22
• Myopic (n = 104 eyes)	Median = −19.1‡[IQR = −61.3 to −25.3]	Estimate = −20.0[95% CI = −31.2 to −8.7]	0.005‡

^*Axial length and refractive error shift included as categorical variables in separate linear mixed models, with subfoveal choroidal thickness as the outcome measure and adjusted for sex and ethnicity.

^†Refractive error shift determined as a change in spherical equivalent of 0.50 D over the 8-year period.

^‡Statistically significant at P < 0.05.

ChT, choroidal thickness; CI, confidence interval; IQR, interquartile range.