Table 2.

Logistic Regression Analysis Investigating the Association of RTL (Decrease by 0.1) and AMD Using Various Adjustment Models^*

	All (N = 2262)		Women† (n = 1185)		Men† (n = 1077)
RTL	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
Model 1 unadjusted	1.13 (1.07–1.19)	<0.001	1.19 (1.10–1.28)	<0.001	1.07 (0.99–1.16)	0.08
Model 2 adjusted for sex	1.13 (1.08–1.20)	<0.001	—		—
Model 3 adjusted for age and sex	1.08 (1.02–1.14)	0.005	1.14 (1.06–1.23)	<0.001	1.01 (0.93–1.10)	0.76
Model 4 adjusted for age, sex, and current smoking	1.08 (1.02–1.14)	0.007	1.14 (1.05–1.22)	<0.001	1.01 (0.93–1.10)	0.76
Model 5 adjusted for age, sex, current smoking, HDL cholesterol, diabetes, cardiovascular disease, and hypertension	1.07 (1.01–1.14)	0.016	1.12 (1.04–1.22)	0.003	1.02 (0.93–1.11)	0.73

^*N refers to the participants with available RTL measurements and AMD classification status. Of the 2262 participants, 1635 showed no signs of AMD, and 627 participants had either early or late AMD according to the Three Continent AMD Consortium Severity Scale.

^†Sex-specific models are not adjusted for sex.