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. 2022 May 16;13:848957. doi: 10.3389/fphar.2022.848957

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Copyright © 2022 Ding, Lu, Wang, Xiang, Hu, Lin, Ding, Xiao and Gong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transcriptome analysis of astilbin-treated CD4⁺ T cell functions. (A) Top 10 changed genes in biological process, cellular component, and molecular function. (B) Numbers of differentially expressed genes in molecular function by gene ontology analysis. GSEA of signaling molecules involved in antioxidant activity (C) and T cell activation (D). Heatmap of upregulated (E) or downregulated (F) genes involved in immune function.