Table 3.
Encephalitis cases identified through different surveillance methods and case definitions, including sensitivity, specificity and positive predictive value (PPV)
| Method | Recruitment case definition | Study case definition | Review panel | Sensitivity % (95% CI) | Specificity % (95% CI) | PPV |
|---|---|---|---|---|---|---|
| HSV daily list | 102 (90%) | 19 (95%) | 6 (86%) | 86% (60–112) | 9% (4–15) | 6% |
| ICD-10 daily admission list | 11 (10%) | 1 (5%) | 1 (14%) | 14% (12–40) | 91% (85–96) | 9% |
| Clinician reporting | 3 (3%) | 1 (5%) | 1 (14%) | 14% (12–40) | 98% (96–101) | 33% |
| Total* | 113 | 20 | 7 | − | − | − |
CI, Confidence interval.
*
A small number of patients were identified through multiple sources (see text), hence totals may not summate.