Table 3.

Time-dependent multivariate analysis of Helicobacter pylori risk

Nature of event …	H. pylori acquisition after initial negative H. pylori biopsy	H. pylori persistence after initial positive H. pylori biopsy	H. pylori re-infection or relapse after cure
No. events/initial no. at risk (%) …	56/603 (9·3%)	195/319 (61·1%)	20/68 (29·4%)
	HR (95% CI)	HR (95% CI)	HR (95% CI)
Age at initial biopsy	1·013 (0·996–1·030)	1·001 (0·995–1·007)	0·945 (0·853–1·047)
Female sex	0·816 (0·475–1·403)	0·891 (0·866–1·192)	0·343 (0·132–0·892)*
Yearly period at initial biopsy	0·988 (0·936–1·044)	0·979 (0·952–1·007)	0·983 (0·879–1·100)
Non-European origin	3·686 (1·805–7·525)†	0·830 (0·564–1·221)	0·527 (1·189–1·465)

HR, Hazard ratio; CI, confidence interval.

^†P < 0·001.

^*P = 0·028.