Table 4.
Comparison of Helicobacter pylori non-susceptibility in paired samples at initial and at last biopsies in subjects stratified by geographical origin
| Clarithromycin non-susceptibility | |||||
|---|---|---|---|---|---|
| Initial biopsy | Last biopsy | Total | |||
| European | Non-European | ||||
| Non-susceptible | 100·0% (4/4) | 80·8% (21/26) | 83·3% (25/30) | ||
| Susceptible | 6·7% (2/30) | 10·7% (21/196) | 10·2% (23/226) | ||
| Fisher's exact test | P < 0·001 | P < 0·001 | P < 0·001 | ||
| OR (95% CI) | Indeterminate | 35·0 (11·9–102·6) | 44·1 (15·4–126·4) | ||
| Metronidazole non-susceptibility | |||||
| Initial biopsy | European | Non-European | Total | ||
| Non-susceptible | 80·0% (8/10) | 82·4% (42/51) | 82·0% (50/61) | ||
| Susceptible | 17·9% (5/28) | 11·8% (23/195) | 12·6% (28/223) | ||
| Fisher's exact test | P = 0·001 | P < 0·001 | P < 0·001 | ||
| OR (95% CI) | 18·4 (3·0–114·3) | 34·9 (15·0–80·9) | 31·7 (14·8–67·9) | ||
OR, Odds ratio; CI, confidence interval.
Percentages of susceptibility and of non-susceptibility to either antibiotic at initial biopsy did not differ in European children and in non-European children (P > 0·10).