Table 4.
Association between herpes simplex and subsequent malignancy: estimated age-adjusted hazard ratios according to age group, site and gender
| Age (no. of events in men + women) | Site | Men HR (95% CI) | Women HR (95% CI) |
|---|---|---|---|
| All (70 + 88) | All | 0·91 (0·49–1·70) | 1·06 (0·64–1·74) |
| ⩽50 (5 + 32) | All | 0·80 (0·08–8·08) | 1·17 (0·52–2·63) |
| 51–65 (30 + 28) | All | 1·01 (0·41–2·46) | 0·85 (0·33–2·18) |
| >65 (35 + 28) | All | 0·68 (0·35–2·11) | 1·18 (0·49–2·87) |
| >65 (11 + 0) | Lung | 0·84 (0·18–3·97) | † |
| >65 (9 + 0) | Prostate | ‡ | † |
| >65 (0 + 8) | Breast | † | 1·18 (0·24–5·82) |
| >65 (1 + 7) | Colorectal | † | 1·42 (0·24–8·54) |
| >65 (6 + 7) | Haematological | 2·06 (0·37–11·56) | 1·48 (0·29–7·44) |
HR, Hazard ratio; CI, confidence interval.
†
No cases of malignancy were recorded in at least one of the comparison groups.
‡
Only one case of malignancy was recorded in at least one of the comparison groups.