Table 1.
Comparison Between Optical Imaging Technologies and Traditional Clinical Imaging Modalities in Clinical Application of Tumor Disease
| Imaging Modality | Depth of Penetration | Resolution | Speed | Price | Safety |
|---|---|---|---|---|---|
| PET | No limit | 1–2 mm | Sec-min | **** | Ionizing radiation |
| ECT | No limit | 0.3–1 mm | Sec-min | **** | Ionizing radiation |
| CT | No limit | 0.2 mm | Min | ** | Ionizing radiation |
| MRI | No limit | 100–500 µm | Min-hour | **** | Strong magnetic field |
| US | mm-cm | 100–500 µm | Sec-min | * | Safe |
| RSI | mm | 10–500 µm | Sec-min | * | Safe |
| FLI | mm | 10–500 µm | Sec-min | * | Safe |
| PAI | mm-cm | 10–500 µm | Sec-min | * | Safe |
Note: *$500,000 (Instrument cost).
Abbreviations: PET, positron emission tomography; ECT, emission computed tomography; CT, computed tomography; MRI, magnetic resonance imaging; US, ultrasound; RSI, raman spectroscopy; PAI, photoacoustic imaging; FLI, fluorescence imaging.