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. 2020 Nov 2;111(6):595–603. doi: 10.1007/s00392-020-01764-0

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Renal renin arteriovenous difference following a hypotensive challenge before and after RDN. At baseline (prior to RDN) and before termination (after RDN), the treatment group animals underwent a hypotensive challenge. Blood samples from the renal artery and vein were drawn before and after the hypotensive challenge. Renin concentrations were measured using a porcine renin ELISA kit (NeoBiolab, Cambridge, MA, USA) and renal renin arteriovenous difference (AV-Δ) was calculated by subtracting the arterial from venous renin concentration. Complete renin secretion data was available in 6 animals at baseline and termination