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. 2022 Feb 11;34(6):1429–1438. doi: 10.1007/s40520-022-02087-y

Table 2.

Predictors of LVEF recovery in patients with baseline reduced LVEF

Univariate Multivariate
OR (95% CI) P value OR (95% CI) P value
Age, years 0.99 (0.98–1.01) 0.222
Male 0.80 (0.51–1.25) 0.324
Hypertension 0.99 (0.70–1.39) 0.935
Diabetes 0.79 (0.56–1.11) 0.170
Prior PCI 0.88 (0.30–2.57) 0.815
Smoking 1.02 (0.72–1.43) 0.918
Anterior MI 0.37 (0.25–0.53)  < 0.001 0.55 (0.36–0.84) 0.006
Killip class II–IV 0.72 (0.45–1.15) 0.164
SBP (per 10 mmHg increase) 0.99 (0.92–1.05) 0.689
Heart rate (per 10 bpm increase) 0.84 (0.77–0.92)  < 0.001 0.88 (0.79–0.98) 0.021
Out-of-hospital cardiac arrest 2.07 (0.80–5.34) 0.133
Multivessel disease 1.11 (0.79–1.56) 0.549
TIMI flow 0–1 before PCI 0.74 (0.51–1.06) 0.102
Usage of IABP 0.69 (0.39–1.23) 0.210
Baseline LVEF (per 5% increase) 1.88 (1.60–2.20)  < 0.001 1.71 (1.45–2.02)  < 0.001
Initial creatinine, umol/L 1.00 (0.99–1.00) 0.122
Peak Troponin T, ng/mL 0.86 (0.82–0.90)  < 0.001 0.85 (0.81–0.90)  < 0.001
ACEIs/ARBs 1.22 (0.86–1.71) 0.264
β-receptor blockers 0.59 (0.38–0.92) 0.020 0.79 (0.47–1.33) 0.378

OR odds ratio, 95% CI 95% confidence interval, LVEF Left ventricular ejection fraction, PCI Percutaneous coronary intervention, MI myocardial infarction, SBP Systolic blood pressure, TIMI Thrombolysis in Myocardial Infarction, IABP Intra-aortic balloon pump, ACEIs Angiotensin-converting enzyme inhibitors, ARBs Angiotensin II receptor blockers