Table 4b.

Results of the diagnostic methods used for the detection of MAP infection in tissue samples (number of positive tissue samples)

Substudy	Tissue	n*	Number of positive samples
			Bacterial microscopy	Isolation	Histology	Immuno- histochemistry†
1	Ileum	50	45	48	48	46
	Jejunum	50	42	48	47	43
	Mesenteric Ln	50	44	49	48	46
	Caecal Ln	50	43	48	47	43
2	Ileum	150	0	19	5	0
	Jejunum	150	0	16	3	0
	Mesenteric Ln	150	1	21	10	0
	Caecal Ln	150	1‡	24	4	0

MAP, Mycobacterium avium ssp. paratuberculosis; Ln, lymph node.

^*Number of tissues examined.

^†Immunohistochemical labelling of Mycobacterium spp.

^‡MAP infection could not be confirmed with other methods.