Table 3.

Associations between the latent variable of PASC symptoms and objective signs of organ system dysfunction

	Latent variable of PASC symptoms
Objective signs of dysfunction	Coefficient	p	95% CI
Weight loss (⩽ 5% of BMI value prior to COVID-19)a	0.258	0.003	0.090	0.426
Reduced resting oxygen saturation (⩽92%)	0.200	0.211	–0.113	0.513
Decreased oxygen saturation during effortb	0.029	0.985	–0.303	0.309
Reduced number of repetitions during sit-to-stand test	0.577	<0.001	0.382	0.772
Reduced handgrip strength	0.243	0.007	0.065	0.420
COVID-related abnormalities at X-ray	–0.031	0.727	–0.208	0.145
FVC <80% of predicted at spirometry test	–0.27	0.760	–0.202	0.147
eGFR lower than 60 ml/min/1.73 m2 (in subjects with no previous history of kidney disease)c	0.141	0.277	–0.113	0.394

CI, confidence intervals; BMI, body mass index; FVC, forced vital capacity; eGFR, estimated glomerular filtration rate.

^aDifference between current BMI measurement and calculated BMI based on self-reported estimates of body weight prior to COVID-19.

^bOxygen saturation reduction of ⩾4 points during sit-to-stand test (not undertaken in subjects presenting resting pulse oximetry ratings lower than 90%).

^cEstimated glomerular filtration rate calculated according to CKD EPI³⁰.