Table 1.
Comprehensive performance of each method in real-world scRNA-seq datasets with experimentally annotated doublets.
| PAUC800 | PAUC900 | PAUC950 | PAUC975 | AUC | PR | |
|---|---|---|---|---|---|---|
| bcds | 0.598456581 | 0.697609168 | 0.747471204 | 0.772440146 | 0.797428571 | 0.465471429 |
| Chord | 0.602189241 | 0.701382997 | 0.751248502 | 0.77621856 | 0.801214286 | 0.464642857 |
| ChordP | 0.614164051 | 0.713609623 | 0.763485434 | 0.788453732 | 0.8132 | 0.466514286 |
| cxds | 0.576279854 | 0.675031498 | 0.724828357 | 0.749788808 | 0.774785714 | 0.367342857 |
| doubletCells | 0.396983835 | 0.487445535 | 0.535271112 | 0.559821949 | 0.584685714 | 0.173985714 |
| DoubletDetection | 0.569370526 | 0.666356657 | 0.715610186 | 0.740426505 | 0.793114286 | 0.500857143 |
| DoubletFinder | 0.537830717 | 0.636466839 | 0.686221775 | 0.711172069 | 0.736171429 | 0.339428571 |
| Scrublet | 0.564203075 | 0.663581473 | 0.713449225 | 0.738419459 | 0.763414286 | 0.399771429 |
| Solo | 0.604236942 | 0.703224153 | 0.752987364 | 0.777930394 | 0.803142857 | 0.434714286 |
The average performance of various methods in all datasets. The indexes are the pAUC800, pAUC900, pAUC950, pAUC975, AUC and AUPRC.