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. 2022 May 30;13:3009. doi: 10.1038/s41467-022-30594-z

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Schematic illustration of a NIRS probe and wireless module depolyed in a microsurgically transferred free muscular flap. b Exploded view of the wireless communication module based on Bluetooth Low Energy (BLE) technology. c Top-down view of the sensing probe featuring the bioresorbable barbs and sensing units. d Image of a wireless NIRS system with sensing probe wrapped around a plastic tube to highlight its mechanical flexibility. e Enlarged view of the wireless communication module supported on a flexible printed circuit board. f Images of the sensing probe, top: side view, bottom: top-down view. g Exploded view of the sensing probe with a conformal layer of parylene for encapsulation and a bioresorbable base layer consisting of distributed bioresorbable barbs for temporarily anchoring the probe to the surrounding soft tissues.