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. 2021 Jun 11;36(6):1185–1193. doi: 10.1038/s41433-021-01612-z

Table 2.

Comparison of cell densities at different corneal layers of patients during aromatase inhibitor therapy.

Pre-treatment (n = 13 eyes) Median (min-max) At 3. month (n = 13 eyes) Median (min-max) At 6. month (n = 13 eyes) Median (min-max) P

Basal epithelium,

cells/mm²

3692 (2377–5771) 3184 (1892–4700) 3045 (1465–3950) <0.001*

Anterior stroma,

cells/mm²

382 (203–486) 340 (270–400) 311 (255–451) 0.01*

Posterior stroma,

cells/mm²

395 (201–565) 370 (217–543) 322 (217–434) 0.002*

Endothelium,

cells/mm²

2281 (1276–3011) 2119 (1095–2850) 1987 (1166–2826) 0.004*
Endothelial polymegethism rate/% 41.6 (32–66.1) 47.2 (28.9–79.1) 46.7 (27–70.5) 0.39
Endothelial pleomorphism rate/% 50 (25–65) 44.4 (15.5–60) 42.8 (14.7–72) 0.04*

*Statistically significant.