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. 2021 Jun 11;36(6):1185–1193. doi: 10.1038/s41433-021-01612-z

Table 3.

Comparison of sub-basal nerve plexus densities of patients during the aromatase inhibitor therapy.

Pre-treatment (n = 13 eyes) Median (min-max) At 3. month (n = 13 eyes) Median (min-max) At 6. month (n = 13 eyes) Median (min-max) P
Number of long nerves fibres, nerves/frame 3 (2–6) 2 (1–6) 2 (1–4) <0.001*
Total number of nerves, nerves/frame 5 (2–8) 4 (2–7) 4 (2–5) <0.001*
Total nerve density, mm/frame 1148.87 (955.32–3184.74) 1065 (629.52–2543.45) 995.56 (543.49–2245.56) <0.001*
Tortuosity 1 (1–1) 1 (1–2) 2 (1–2) 0.004*

*Statistically significant.