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. 2022 May 30;12:8991. doi: 10.1038/s41598-022-13008-4

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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(a) Modular breath sampler. During sampling, the patient breathes through the mouthpiece; inhaling (I) and exhaling (II). The exhaled air is guided through the sampler to the diffuser into the capture buffer. The exhaled air leaves the sampler on the back end. After sampling, the collection tube can be disconnected and stored for analysis. (b) Correlation plot depicting SARS-CoV-2 viral RNA load measured in nasopharyngeal throat swab and saliva samples. (c) SARS-CoV-2 RNA detection in exhaled air samples and nasopharyngeal throat swab samples. Filled dots () represent cases in which SARS-CoV-2 RNA was detected in exhaled air samples. Open dots (○) represent cases in which SARS-CoV-2 RNA was not detected.

Inline graphic — (a) Modular breath sampler. During sampling, the patient breathes through the mouthpiece; inhaling (I) and exhaling (II). The exhaled air is guided through the sampler to the diffuser into the capture buffer. The exhaled air leaves the sampler on the back end. After sampling, the collection tube can be disconnected and stored for analysis. (b) Correlation plot depicting SARS-CoV-2 viral RNA load measured in nasopharyngeal throat swab and saliva samples. (c) SARS-CoV-2 RNA detection in exhaled air samples and nasopharyngeal throat swab samples. Filled dots () represent cases in which SARS-CoV-2 RNA was detected in exhaled air samples. Open dots (○) represent cases in which SARS-CoV-2 RNA was not detected.