Skip to main content
. 2022 May 17;12:858379. doi: 10.3389/fonc.2022.858379

Figure 2.

Figure 2

IFNγ treatment promotes aerobic glycolysis and tryptophane metabolism in A498 and 786-O. (A) The heat maps indicate a distinct metabolic rewiring following IFNγ treatment in A498 and 786-O cells as compared to controls. n=3 for each group. (B) Comparative analysis of metabolites of glycolysis, PPP (pentose phosphate pathway), TCA cycle (tricarboxylic acid), and energy metabolites between IFNγ treated and control A498 and 786-O cells. Putative metabolites which were assigned on the basis of m/z and MT in HMT standard compound library. The ratio is computed by using averaged detection values. The latter was used as denominator. The p-value is computed by Welch’s t-test (*p<0.05, **p<0.001). N.A., not applicable.