TABLE 2.
The β and 95% CI of plasma Se concentrations by demographic factors in Chinese middle-aged and elderly adults with hypertension stratified by sex.
| Variables | N | Plasma Se, μ g/L | Crude Model* |
Adjusted Model† |
||
| β (95% CI) | p | β (95% CI) | p | |||
| Male | ||||||
| Age, years | ||||||
| <60 | 597 | 79.4 ± 19.0 | 0.00 (Ref) | 0.00 (Ref) | ||
| 60 to <70 | 353 | 76.1 ± 20.3 | −3.35 (−6.08, −0.62) | 0.016 | −2.30 (−5.02, 0.42) | 0.097 |
| ≥70 | 439 | 71.2 ± 23.3 | −8.17 (−10.73, −5.61) | <0.001 | −6.65 (−9.51, −3.78) | <0.001 |
| p, for trend | <0.001 | <0.001 | ||||
| Region | ||||||
| Se-rich | 227 | 89.3 ± 18.5 | 0.00 (Ref) | 0.00 (Ref) | ||
| Se-sufficient | 779 | 75.1 ± 18.7 | −14.15 (−17.12, −11.18) | <0.001 | −15.02 (−18.29, −11.75) | <0.001 |
| Se-marginal | 383 | 69.8 ± 23.4 | −19.50 (−22.79, −16.20) | <0.001 | −19.82 (−23.44, −16.21) | <0.001 |
| p, for trend | <0.001 | <0.001 | ||||
| BMI, kg/m2 | ||||||
| ≥28 | 267 | 78.2 ± 20.7 | 0.00 (Ref) | 0.00 (Ref) | ||
| 24 to <28 | 624 | 76.4 ± 20.2 | −1.82 (−4.83, 1.19) | 0.237 | −2.09 (−4.94, 0.76) | 0.150 |
| <24 | 498 | 74.2 ± 22.1 | −3.99 (−7.12, −0.87) | 0.012 | −3.59 (−6.67, −0.50) | 0.022 |
| p, for trend | 0.009 | 0.023 | ||||
| Female | ||||||
| Age, years | ||||||
| <60 | 459 | 75.0 ± 19.9 | 0.00 (Ref) | 0.00 (Ref) | ||
| 60 to <70 | 311 | 72.9 ± 22.9 | −2.11 (−5.14, 0.91) | 0.170 | −2.65 (−5.56, 0.25) | 0.073 |
| ≥70 | 440 | 69.7 ± 20.6 | −5.33 (−8.07, −2.58) | <0.001 | −4.79 (−7.59, −2.00) | <0.001 |
| p, for trend | <0.001 | <0.001 | ||||
| Region | ||||||
| Se-rich | 173 | 88.4 ± 16.3 | 0.00 (Ref) | 0.00 (Ref) | ||
| Se-sufficient | 684 | 72.7 ± 20.2 | −15.71 (−19.01, −12.41) | <0.001 | −15.92 (−19.60, −12.24) | <0.001 |
| Se-marginal | 353 | 64.5 ± 20.4 | −23.95 (−27.54, −20.35) | <0.001 | −21.77 (−25.81, −17.72) | <0.001 |
| p, for trend | <0.001 | <0.001 | ||||
| BMI, kg/m2 | ||||||
| ≥28 | 226 | 74.2 ± 19.7 | 0.00 (Ref) | 0.00 (Ref) | ||
| 24 to <28 | 488 | 71.8 ± 20.5 | −2.40 (−5.72, 0.93) | 0.237 | −2.96 (−6.06, 0.14) | 0.061 |
| <24 | 496 | 72.6 ± 22.3 | −1.65 (−4.96, 1.67) | 0.012 | −3.07 (−6.22, 0.08) | 0.056 |
| p, for trend | 0.492 | 0.093 | ||||
For continuous variables, the values are presented as mean ± SD.
1Se-marginal areas in China include four provinces (Gansu, Heilongjiang, Liaoning, and Shandong), Se-sufficient areas in China include eight provinces (Anhui, Beijing, Hebei, Jiangsu, Ningxia, Shanxi, Sichuan, and Yunnan), and Se-rich areas in China include two provinces (Guangxi and Hunan).
*Values for β and 95% CI are from multilinear regression analysis.
†If not stratified, the model was adjusted for sex, age, region (Se-marginal, Se-sufficient, and Se-rich areas), BMI, SBP, DBP, history of hypertension, antihypertensive drug use, multivitamin use, smoking, alcohol drinking, meat consumption, and consumption of fruits and vegetables.