Table 1.
Baseline and follow-up parameters after IASD implantation.
| Parameter | Baseline (March 2015) | Follow-up (April 2021) |
|---|---|---|
|
Hemodynamic study |
20 March 2015 |
7 April 2021 |
| Mean RA, mmHg | 10 | 7 |
| Mean PAP, mmHg | 28 | 27 |
| Mean PCWP, mmHg | 18 | 17 |
| Systolic Ao, mmHg | 148 | 137 |
| Diastolic Ao, mmHg | 58 | 47 |
| Mean Ao, mmHg | 81 | 80 |
| PAR, dyn | 118.4 | 76 |
| PAR, Wood units | 1.5 | 1.0 |
| CO, thermodilution, L/minute | 6.75 | 10.52 |
| CI, L/minute/m2 | 3.02 | 4.93 |
| Qp/Qs | 1.18 after implantation of IASD | |
| Qp/Qs | 1.22 (at 6 months) | |
| Qp/Qs | 1.36 (at 6 years) | |
|
CMR |
9 March 2015 |
2 September 2015 |
| LVEF | 61% | 71% |
| LVEDV, mL | 142 | 139 |
| LVESV, mL | 56 | 59 |
| LVEDVi, mL/m2 | 64 | 63 |
| LVESVi, mL/m2 | 56 | 59 |
| RVEF | 65% | 68% |
| RVEDV, mL | 137 | 139 |
| RVESV, mL | 49 | 59 |
| RVEDVi, mL/m2 | 61 | 63 |
| RVESVi, mL/m2 | 22 | 32 |
| LA, mL | 81 | 79 |
| RA, mL | 65 | 72 |
| LAi, mL/m2 | 36 | 35 |
| RAi, mL/m2 | 22 | 32 |
|
TTE |
11 March 2015 |
6 April 2021 |
| LVEF | 60% | 60% |
| LVEDD, mm | 51 | 54 |
| LVESD, mm | 36 | 39 |
| RVEDD, mm | 27 | 30 |
| TAPSE, mm | 17 | 20 |
| PW Doppler E wave, cm/s | 80 | 90 |
| PW Doppler A wave, cm/s | 50 | 60 |
| TDI É sept, cm/s | 5 | 5 |
| TDI É lat, cm/s | 7 | 10 |
| E/A | 1.6 | 1.5 |
| E/É | 13.3 | 12 |
| MR grade | 1+ | 1+ |
| TR grade | 1+ | 1+ |
| TRI gradient | 32 | 37 |
| IVC – expiration, mm | 20 | 21 |
|
Oral diuretic dose, mg/day |
Baseline |
Follow-up |
| Furosemide | 60 | 250 |
| Spironolactone | 25 | 100 |
| Hydrochlorothiazide | 12.5 | 12.5 |
IASD, interatrial shunt device; RA, right atrial pressure; PAP, pulmonary artery pressure; PCWP, pulmonary capillary wedge pressure; Ao, aortic pressure; PAR, pulmonary arterial resistance; CO, cardiac output; CI, cardiac index; Qp/Qs, ratio of pulmonary blood flow to systemic blood flow; CMR, cardiac magnetic resonance imaging; LVEF, left ventricular ejection fraction; LVEDV, left ventricular end-diastolic volume; LVESV, left ventricular end-systolic volume; LVEDVi, left ventricular end-diastolic volume index; LVESVi, left ventricular end-systolic volume index; RVEF, right ventricular ejection fraction; RVEDV, right ventricular end-diastolic volume; RVESV, right ventricular end-systolic volume; RVEDVi, right ventricular end-diastolic volume index; RVESVi, right ventricular end-systolic volume index; LA, left atrial volume; LAi, left atrial volume index; RA, right atrial volume; RAi, right atrial volume index; TTE, transthoracic echocardiography; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; RVEDD, right ventricular end-diastolic diameter; TAPSE, tricuspid annulus posterior systolic excursion; PW, pulsed wave; E wave, velocity of early filling at diastole in left ventricle; A wave, velocity of left atrial contraction; TDI, tissue Doppler imaging; É sept, velocity of septal mitral annulus assessed by TDI; É lat, velocity of lateral mitral annulus assessed by TDI; E/A, ratio of E and A waves; E/É, ratio of E wave and mean of É sept and É lat; MR, mitral regurgitation; 1+, trivial; TR, tricuspid regurgitation; TRI gradient, systolic gradient of tricuspid regurgitation; IVC, inferior vena cava.