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. 2022 May 17;9:837848. doi: 10.3389/fsurg.2022.837848

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Copyright © 2022 Zheng, Wang, Li, Zhang, Chen and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differences of immuno-infiltrative features between the two risk subgroups. (A) Levels of 22 immunocytes calculated with CIBERSORT in two risk subgroups. (B) Levels of ImmuneScore, StromalScore, ESTIMATEScore, and TumorPurtiy calculated with ESTIMATE in the two risk subgroups. (C) Heatmap indicating the differences in ssGSEA scores between two risk subgroups. (D) Expression levels of PD-1 and PD-L1 in two risk subgroups. (E) Associations between calculated risk scores and PR clusters. (F) Alluvial diagram displaying the changes in the risk score, PR clusters, survival status, cinical stage, and TNM stage in TCGA-BRCA cohort. *p < 0.05, **p < 0.01, ***p < 0.001, ns, not significant.