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. 2022 May 17;13:883057. doi: 10.3389/fphar.2022.883057

FIGURE 2.

FIGURE 2

EPO alleviated mitochondrial dysfunction and apoptosis in mesangial cells exposed to HG. (A) Representative images of mesangial cells stained with Mitotracker-Red. Representative immunoblots and quantification of (B) Drp-1 and (C) Mfn-2. Representative images of mesangial cells stained with (D) JC-1 and (E) MitoSOX as well as (G) quantification of the level of mitochondrial ROS. (F) Flow cytometry analysis and (H) quantitative analysis of cell apoptosis. Values are presented as mean ± SEM, n = 3. **p < 0.01 vs. Control group; # p < 0.05, ## p < 0.01 vs. HG group.