Table 1.
Baseline information of the overall population* .
|
Total
(n = 117,056) |
Normotension
(n = 99,526) |
Hypertension
(n = 17,530) |
p value | |
|---|---|---|---|---|
| Age (years) | 41 (34–53) | 39 (33–50) | 53 (41–63) | <0.001 |
| Female (%) | 54,099 (46.2) | 48,304 (48.5) | 5,795 (33.1) | <0.001 |
| Current smoker (%) | 6,674 (5.7) | 5,520 (5.5) | 1,154 (6.6) | <0.001 |
| Current drinker (%) | 872 (0.7) | 651 (0.6) | 221 (1.3) | <0.001 |
| Family history of diabetes (%) | 2,651 (2.3) | 2,367 (2.4) | 284 (1.6) | <0.001 |
| BMI (kg/m2) | 23.2 (21–25.5) | 22.9 (20.8–25.1) | 25.1 (23–27.3) | <0.001 |
| FPG (mmol/L) | 5.0 (4.61–5.35) | 4.95 (4.6–5.3) | 5.19 (4.8–5.62) | <0.001 |
| ALT (U/L) | 18.2 (13–27.8) | 18 (12.9–26.8) | 22 (15.7–33) | <0.001 |
| AST (U/L) | 22.0 (18.7–26.9) | 21.8 (18.2–26) | 24.2 (20.7–29.7) | <0.001 |
| BUN (mmol/L) | 4.57 (3.85–5.4) | 4.53 (3.81–5.35) | 4.78 (4.06–5.63) | <0.001 |
| Scr (μmol/L) | 71.3 (59.3–83.0) | 70.5 (58.8–82.4) | 75.8 (64.23–86.0) | <0.001 |
| Lipid profiles and atherosclerotic indices | ||||
| TC (mg/dl) | 181.70 (159.67–204.90) | 179.77 (158.51–202.97) | 191.75 (168.56–216.50) | <0.001 |
| TG (mg/dl) | 97.46 (67.34–146.19) | 97.46 (67.34–146.19) | 97.46 (67.34–147.08) | 0.772 |
| LDL (mg/dl) | 104.38 (88.53–121.78) | 103.22 (87.76–120.62) | 110.95 (93.94–128.74) | <0.001 |
| HDL-c (mg/dl) | 51.80 (45.23–59.92) | 52.19 (45.23–59.92) | 51.42 (44.46–59.15) | <0.001 |
| Non-HDL-c (mg/dl) | 127.96 (108.25–151.16) | 126.03 (106.70–148.84) | 138.40 (117.53–162.37) | <0.001 |
| AC | 2.43 (1.95–3.1) | 2.38 (1.91–3.04) | 2.72 (2.21–3.46) | <0.001 |
| AIP | 0.28 (0.1–0.47) | 0.28 (0.10–0.46) | 0.29 (0.11–0.48) | <0.001 |
*
Continuous data are expressed as median (interquartile range) due to the skewed distribution. The p-value is a comparison between the normotension and hypertension groups. FPG, fasting plasma glucose; TG, triglycerides; TC, total cholesterol; HDL-c, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; AC, atherogenic coefficient; AIP, atherogenic risk of plasma; Scr, serum creatinine; BUN, blood urea nitrogen; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index.