TABLE 2.
The lipid metabolism and urea cycle related genes altered in NFIB knock out liver.
| Gene | Biological process | Fold change | p |
|---|---|---|---|
| ACSS2 | Lipid biosynthetic process | 1.85 | 0.028 |
| FASN | Fatty acid synthesis | 1.73 | 0.000 |
| PNPLA3 | Lipid catabolic process | 1.71 | 0.035 |
| ADORA1 | Lipid catabolic process | 1.61 | 0.029 |
| CES1G | Lipid catabolic process | 1.59 | 0.028 |
| Mid1ip1 | Lipid biosynthetic process | 1.54 | 0.010 |
| ACLY | Lipid biosynthetic process | 1.53 | 0.006 |
| CES3a | Lipid catabolic process | 0.57 | 0.038 |
| Insig2 | Inhibiting cholesterol biosynthesis | 0.56 | 0.001 |
| ACS2 | Lipid catabolic process | 0.32 | 0.027 |
| CES4a | Lipid catabolic process | 0.06 | 0.005 |
| CPS1 | Urea cycle | 1.69 | 0.007 |
| ASS1 | Urea cycle | 1.51 | 0.007 |
| ASL | Urea cycle | 1.63 | 0.019 |
| ARG1 | Urea cycle | ns | ns |
| OTC | Urea cycle | ns | ns |