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. 2022 May 17;12:838405. doi: 10.3389/fcimb.2022.838405

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Copyright © 2022 Severgnini, Morselli, Camboni, Ceccarani, Laghi, Zagonari, Patuelli, Pedna, Sambri, Foschi, Consolandi and Marangoni

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Microbiota characterization according to the vaginal status (H, I or BV). (A) Barplot of average relative abundances at genus level. Genera with rel. ab. ≤1% were grouped in “Others” category; (B) Line plot of average Lactobacillus species abundance per vaginal status; only the 3 most abundant species are represented; (C) Boxplot of Faith’s phylogenetic diversity of the samples (estimated at endpoint) for each vaginal status. Stars above the plots represent statistical significance (p<0.05); (D) Principal Coordinate Analysis (PCoA) based on unweighted Unifrac distance among samples. Each point represents a sample; ellipses are 95% SEM-based confidence intervals; point and ellipses are grouped according to vaginal status; the first and the second coordinate are represented.