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. 2022 May 17;13:882944. doi: 10.3389/fphys.2022.882944

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Copyright © 2022 Desruelle, Maistre, Gaillard, Richard, Tardivel, Martin, Blatteau, Boussuges, Rives, Risso and Vallee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Volcano plot showing metabolomic data in rats (n = 56) according to the pressure exposure. Fecal metabolites over-expressed in control rats are on the left and those of diver rats are on the right. The dashed line shows where p = 0.05 with points above the line having p < 0.05 and points below the line having p > 0.05. Colors of the dots are in accordance with the Venn diagram and whose significance is true according to the 2-way ANOVA. Red dots are for Diet*Pressure*Interaction, for example. Grey dots are not significant according to the 2-way ANOVA and the post-hoc testes.