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. 2022 May 23;2022:2539871. doi: 10.1155/2022/2539871

Table 2.

The effect of the inclusion of ZnT8-Ab assays in the panel of routinely auto-Abs on the sensitivity for beta-cell autoimmunity in type 1 diabetes (T1D) newly diagnosed children.

Diabetic auto-Ab positive individual (1 auto-Ab) Diabetic auto-Ab positive individual (≥1 auto-Ab) Diabetic auto-Ab positive individual (≥2 auto-Ab) Diabetic auto-Ab negative individuals
ICA, GADA, and IA-2A tested No inclusion of ZnT8-Ab 61 (39.10%) 134 (85.90%) 73 (46.79%) 22 (14.10%)
Inclusion of ZnT8-Ab 44 (28.21%) 140 (89.74%) 96 (61.54%) 16 (10.26%)
p value 0.04 0.30 0.008 0.30