Table 2.
The effect of the inclusion of ZnT8-Ab assays in the panel of routinely auto-Abs on the sensitivity for beta-cell autoimmunity in type 1 diabetes (T1D) newly diagnosed children.
| Diabetic auto-Ab positive individual (1 auto-Ab) | Diabetic auto-Ab positive individual (≥1 auto-Ab) | Diabetic auto-Ab positive individual (≥2 auto-Ab) | Diabetic auto-Ab negative individuals | ||
|---|---|---|---|---|---|
| ICA, GADA, and IA-2A tested | No inclusion of ZnT8-Ab | 61 (39.10%) | 134 (85.90%) | 73 (46.79%) | 22 (14.10%) |
| Inclusion of ZnT8-Ab | 44 (28.21%) | 140 (89.74%) | 96 (61.54%) | 16 (10.26%) | |
| p value | 0.04 | 0.30 | 0.008 | 0.30 |