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. 2022 May 17;12:850509. doi: 10.3389/fcimb.2022.850509

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Copyright © 2022 Zhang, Seminario-Vidal, Cohen, Hussaini, Yao, Rutenberg, Kim, Giualiano, Robinson and Sokol

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sign-associated changes in skin microbiota composition at the genus level. (A) The changes in relative abundance at different erythema levels. (B) The increase in relative abundance of Staphylococcus spp. and Haemophilus spp. in lesional skin were positively corelated with erythema. (C) The changes in relative abundance at different skin thickness levels. (D) The increase in relative abundance of Paracoccus sp. in lesional skin was positively correlated with thicker skin. (E) The changes in relative abundance at different level of excoriation. (F) The increase in relative abundance of Gordonia spp. in the lesional skin was positively correlated with excoriation level. (G) changes in relative abundance at different levels of lichenification (H) The increase in relative abundance of Corynebacterium in lesional skin was negatively correlated with lichenification. *P ≤ 0.05; ***P ≤ 0.001.