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. 2022 May 17;12:865320. doi: 10.3389/fcimb.2022.865320

Figure 1.

Figure 1

Synergistic effects of LipoLLA with antibiotics against H. pylori. The MICs of LipoLLA and four antibiotics against H. pylori were significantly decreased after the combination of LipoLLA with AMX, MTZ, LVFX and CAM respectively. (A) After AMX was used in combination with LipoLLA, MICs of AMX(A(A)) and LipoLLA(A(B)) were significantly reduced compared with the two alone. (B) When LipoLLA was combined with MTZ, the MICs of MTZ(B(A)) and LipoLLA(B(B)) decreased significantly with alone. (C) When LipoLLA was combined with LVFX, MICs of LVFX(C(A)) and LipoLLA(C(B)) were significantly reduced compared with the two alone. (D) After CAM combined with LipoLLA, the MICs of CAM(D(A)) and LipoLLA(D(B)) decreased significantly with alone. AMX (alone), the MICs of amoxicillin against 30 H. pylori strains when used alone; AMX (combination), the MICs of amoxicillin against 30 H. pylori strains when combined with LipoLLA; LipoLLA (alone), the MICs of LipoLLA against 30 H. pylori strains when used alone; LipoLLA (combination), the MICs of LipoLLA against 30 H. pylori strains when combined with amoxicillin. ***P<0.001.