Table 1.
MICs of LipoLLA, AMX, MTZ, LVFX and CAM against H. pylori strains.
| strains | MIC(μg/mL) | ||||
|---|---|---|---|---|---|
| LipoLLA | AMX | MTZ | LVFX | CAM | |
| S1 | 7.500 | 0.016 | 1.000 | 0.250 | 0.063 |
| S2 | 7.500 | 0.016 | 1.000 | 0.125 | 0.063 |
| S3 | 7.500 | 0.016 | 4.000 | 0.032 | 0.125 |
| S4 | 7.500 | 0.016 | 1.000 | 0.032 | 0.063 |
| S5 | 7.500 | 0.032 | 2.000 | 0.250 | 0.063 |
| MTZ1 | 7.500 | 0.016 | 8.000 | 0.032 | 0.063 |
| MTZ2 | 7.500 | 0.063 | 16.000 | 0.125 | 0.063 |
| MTZ3 | 7.500 | 0.032 | 32.000 | 0.250 | 0.500 |
| MTZ4 | 7.500 | 0.016 | 32.000 | 0.250 | 0.063 |
| MTZ5 | 7.500 | 0.016 | 128.000 | 0.250 | 0.063 |
| MTZ6 | 7.500 | 0.016 | 256.000 | 0.250 | 0.063 |
| LVFX1 | 15.000 | 0.032 | 0.500 | 32.000 | 0.125 |
| LVFX2 | 7.500 | 0.016 | 4.000 | 128.000 | 0.063 |
| LVFX3 | 15.000 | 0.016 | 2.000 | 128.000 | 0.063 |
| LVFX4 | 15.000 | 0.016 | 4.000 | 128.000 | 0.016 |
| LVFX5 | 7.500 | 0.016 | 1.000 | 128.000 | 0.063 |
| CAM1 | 7.500 | 0.032 | 2.000 | 0.125 | 8.000 |
| CAM2 | 7.500 | 0.032 | 2.000 | 0.250 | 8.000 |
| CAM3 | 7.500 | 0.016 | 2.000 | 0.125 | 256.000 |
| CAM4 | 7.500 | 0.016 | 2.000 | 0.063 | 256.000 |
| CAM5 | 7.500 | 0.016 | 2.000 | 0.125 | 256.000 |
| DR1 | 7.500 | 0.016 | 2.000 | 2.000 | 1.000 |
| DR2 | 3.750 | 0.016 | 8.000 | 0.250 | 1.000 |
| DR3 | 7.500 | 0.016 | 32.000 | 1.000 | 0.063 |
| MDR1 | 3.750 | 0.016 | 8.000 | 128.000 | 8.000 |
| MDR2 | 7.500 | 0.016 | 32.000 | 128.000 | 8.000 |
| MDR3 | 7.500 | 0.016 | 32.000 | 32.000 | 8.000 |
| MDR4 | 7.500 | 0.063 | 32.000 | 2.000 | 16.000 |
| MDR5 | 7.500 | 0.125 | 256.000 | 128.000 | 8.000 |
| MDR6 | 7.500 | 1.000 | 256.000 | 128.000 | 256.000 |
The MICs of 30 clinically isolated H. pylori strains were determined. 5 sensitive strains (S1-S5), 6 MTZ-resistant strains (MTZ1-MTZ6), 5 LVFX- resistant strains (LVFX1-LVFX5), 5 were CAM-resistant strains (CAM1-CAM5), 3 dual drug-resistance strains (DR1-DR3), and 6 multidrug resistant strains (MDR1-MDR6). MIC, minimum inhibitory concentration; AMX, amoxicillin; MTZ, metronidazole; LVFX, levofloxacin; CAM, clarithromycin; S, sensitive strain; DR, dual drug-resistant strain; MDR, multidrug-resistant strain.