Figure 2.

The vaginal microbiota (cervicovaginal mucus) was characterized in women with symptomatic cervical ectopy with or without HPV infection. (A) Two alpha diversity indexes were calculated, richness (observed species) and shannon. Boxplots depicting the median and interquartile range stratified by HPV infection. Groups were compared using the Wilcoxon Rank Sum test. Both weighted UniFrac (B) and Bray-Curtis dissimilarity (C) were used in conjunction with principal coordinate analysis (PCoA) to visualize microbial communities stratified by HPV infection. Differences in beta diversity were assessed using permutational multivariate analysis of variance (PERMANOVA). Each point was colored according to the HPV type for HPV-pos women and order by the number of HPV types found.