Table 3.

nadA presence in different serogroups of N. meningitidis isolates based on correlation with the class of pilE gene

Serogroup	Isolates tested (N)	nadA PCR+ (%)	nadA PCR+ in class I pilE (%)	nadA PCR+ in class II pilE (%)
A	48*	77·1 (37/48)	0 (0/0)	77·1 (37/48)†
B	35	11·4 (4/35)	0 (0/20)	40 (4/10)‡§
C	43	18·6 (8/43)	0 (0/32)	100 (8/8)†‡§
W135	10	50 (5/10)	0 (0/4)	100 (5/5)‡
X	2	0 (0/0)	0 (0/2)	0 (0/0)
NG	6	0 (0/0)	0 (0/2)	0 (0/0)

^*Consisted of 11 isolates of CC1 and 37 isolates of CC5 (Supplementary Table S1).

^†All of the serogroup A and C isolates, belonging only to the CC5 isolates conserved the nadA gene.

^‡All of the serogroup B, C and W135 isolates, belonging only to the CC11 isolates conserved the nadA gene.

^§Four serogroup B and one serogroup C isolates belonging to CC11 contained one copy of the insertion sequence IS1301.