Table 2.
Mean difference in leukocyte telomere length for selected characteristics of the Multi-Ethnic Study of Atherosclerosis (MESA) study sample, overall and stratified by gender
| Total sample (n = 163) | Female (n = 100) | Male (n = 63) | ||||
|---|---|---|---|---|---|---|
| Mean diff. (s.e.) | P-value | Mean diff. (s.e.) | P-value | Mean diff. (s.e.) | P-value | |
| Age in years | −0·0029 (0·0014) | 0·04 | −0·0030 (0·0018) | 0·094 | −0·0028 (0·0023) | 0·23 |
| Sex | ||||||
| Male | REF | |||||
| Female | 0·0118 (0·0265) | 0·656 | ||||
| Race/ethnicity | ||||||
| White | REF | REF | REF | |||
| Black | −0·0167 (0·0381) | 0·662 | −0·0350 (0·0482) | 0·47 | 0·0270 (0·0622) | 0·666 |
| Hispanic | −0·0123 (0·0331) | 0·712 | 0·0234 (0·0430) | 0·587 | −0·0673 (0·0517) | 0·198 |
| Education | ||||||
| Complete HS/GED or less | REF | REF | REF | |||
| Some college | −0·0450 (0·0297) | 0·131 | 0·0056 (0·0368) | 0·878 | −0·1282 (0·0496) | 0·012 |
| Bachelor's Degree or more | −0·0213 (0·0332) | 0·521 | 0·0108 (0·0425) | 0·8 | −0·0754 (0·0533) | 0·162 |
| Income | ||||||
| <$5000–$24 999 | 0·0233 (0·0334) | 0·486 | −0·0087 (0·0426) | 0·838 | 0·0611 (0·0597) | 0·311 |
| $25 000–$49 999 | 0·0030 (0·0319) | 0·926 | −0·0290 (0·0417) | 0·488 | 0·0370 (0·0529) | 0·488 |
| $50 000–$100 000+ | REF | REF | REF | |||
| Pack-years of smoking | −0·0009 (0·0011) | 0·387 | −0·0041 (0·0018) | 0·025 | 0·0007 (0·0014) | 0·605 |
| BMI (kg/m2) | −0·0030 (0·0023) | 0·196 | −0·0045 (0·0025) | 0·068 | 0·0029 (0·0059) | 0·619 |
| Diabetes mellitus | ||||||
| Normal | REF | REF | REF | |||
| IFG | −0·0125 (0·0450) | 0·781 | −0·0138 (0·0593) | 0·816 | −0·0066 (0·0701) | 0·926 |
| Untreated/treated DM | 0·0396 (0·0437) | 0·366 | −0·0066 (0·0537) | 0·902 | 0·1164 (0·0751) | 0·127 |
| Hormone medication use | ||||||
| No | REF | REF | REF | |||
| Yes | 0·0195 (0·0322) | 0·547 | 0·0249 (0·0342) | 0·469 | −0·1853 (0·1757) | 0·296 |
| Pathogen burden | ||||||
| Low (0–2) | REF | REF | REF | |||
| High (3–4) | −0·0167 (0·0318) | 0·6 | −0·0567 (0·0421) | 0·181 | 0·0245 (0·0498) | 0·624 |
| CMV serostatus | ||||||
| Negative | REF | REF | REF | |||
| Positive | −0·0267 (0·0352) | 0·449 | −0·0998 (0·0548) | 0·072 | 0·0121 (0·0499) | 0·809 |
| HSV serostatus | ||||||
| Negative | REF | REF | REF | |||
| Positive | −0·0095 (0·0461) | 0·836 | −0·1058 (0·0807) | 0·193 | 0·0273 (0·0605) | 0·654 |
| Helicobacter pylori serostatus | ||||||
| Negative | REF | REF | REF | |||
| Positive | 0·0087 (0·0269) | 0·747 | 0·0139 (0·0334) | 0·679 | −0·0002 (0·0456) | 0·997 |
| Chlamydia pneumoniae serostatus | ||||||
| Negative | REF | REF | REF | |||
| Positive | −0·0393 (0·0285) | 0·17 | −0·0635 (0·0330) | 0·058 | 0·0199 (0·0564) | 0·725 |
s.e., standard error.