Table 2.
aEE(n=75) | EoE(n=71) | p value | ||||
---|---|---|---|---|---|---|
Endoscopic findings, EREFSa | ||||||
Longitudinal furrows/ridges. n (%) | 1.000 | |||||
0 | 7 (9.3) | 6 (8.5) | ||||
1 | 68 (90.7) | 65 (91.5) | ||||
Esophageal rings. n (%) | 33 (44) | 37 (52.1) | 0.573 | |||
0 | 42 (56) | 34 (47.9) | ||||
1 | 31 (41.3) | 33 (46.5) | ||||
2 | 2 (2.7) | 3 (4.2) | ||||
3 | 0 (0) | 1 (1.4) | ||||
White exudates. n (%) | 46 (61.3) | 44 (62.0) | 0.943 | |||
0 | 29 (38.7) | 27 (38.0) | ||||
1 | 42 (56) | 41 (57.7) | ||||
2 | 4 (5.3) | 3 (4.2) | ||||
Stricture. n (%) | 0.433 | |||||
0 | 73 (97.3) | 67 (94.4) | ||||
1 | 2 (2.7) | 4 (5.6) | ||||
Edema. n (%) | 1.000 | |||||
0 | 8 (10.7) | 7 (9.9) | ||||
1 | 67 (89.3) | 64 (90.1) | ||||
Inflammatory scoreb, median (min, max) | 3 (1-4) | 3 (1-4) | 0.382 | |||
Fibrostenotic scorec, median (min, max) | 0 (0-3) | 1 (0-4) | 0.875 | |||
Total scored, median (min, max) | 3 (1-6) | 3 (1-8) | 0.920 | |||
Phenotype (Localized)
Location, n (%) |
26 (34.7) | 18 (25.4) | 0.704 | |||
Ut-Lt | 17 (65.4) | 13 (72.2) | ||||
Mt-Lt | 7 (26.9) | 3 (16.7) | ||||
Lt | 2 (7.7) | 2 (11.1) | ||||
Phenotype (Diffuse)
Location, n (%) |
49 (65.3) | 53 (74.6) | 0.512 | |||
Ut-Lt | 7 (14.3) | 5 (9.4) | ||||
Mt-Lt | 24 (49.0) | 23 (43.4) | ||||
Lt | 18 (36.7) | 25 (47.2) | ||||
Other endoscopic findings, n (%) | ||||||
atrophic gastritis | 12 (16.0) | 11 (15.5) | 0.933 | |||
reflux esophagitis (LA classification; N-M/A/B) | 72/1/2 | 64/5/2 | 0.222 | |||
hiatus hernia | 45 (60.0) | 41 (57.7) | 0.782 | |||
pharyngeal abnormal findings | 2 (2.7) | 2 (2.8) | 0.963 | |||
EUS measurement | ||||||
esophageal wall thickness, mm, mean±SD | 3.78±1.11 | 3.90±1.36 | 0.857 | |||
combined mucosa and submucosa layer, mm, mean±SD | 2.50±0.733 | 2.67±0.987 | 0.599 | |||
Helicobacter pylori infection, n (%) | 0.412 | |||||
current infection | 5 (7.9) | 5 (9.6) | ||||
past infection | 11 (17.5) | 14 (26.9) | ||||
negative infection | 47 (74.6) | 33 (63.5) |
*p<0.05
a Maximum score per participant over the three sites.
b The inflammatory score is the sum of the exudate, edema, and furrows scores.
c The fibrostenotic score is the sum of the rings and stricture scores.
d The total score is calculated from the sum of the exudate, edema, furrows, rings, and stricture scores.
aEE: asymptomatic esophageal eosinophilia, EE: esophageal eosinophilia, EoE: eosinophilic esophagitis, LA: Los Angeles, Lt: lower part of the thoracic esophagus, Mt: middle part of the thoracic esophagus, Ut: upper part of the thoracic esophagus