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Progression-free survival with isatuximab (Isa) carfilzomib (K) dexamethasone (d) (Isa-Kd) compared with Kd. (A) Patients with renal impairment (RI) (eGFR <60 mL/min/1.73 m²) or (B) without RI (eGFR ≥60 mL/min/1.73 m²), (ITT population). Progression-free survival (PFS) as per blinded independent response committee. d: dexamethasone; eGFR: estimated glomerular filtration rate; Isa: isatuximab; ITT: intent to treat; K: carfilzomib; PFS: progression-free survival.
