Table 2.

Grade ≥ 3 SAEs

Adverse event	n	%
Rash*	4	11
Pulmonary†	2	6
Arthritis‡	1	3
Graft failure§	1	3
LFT elevation	1	3
Hypertension	1	3
Hypotension	1	3
Acute kidney injury	1	3

SAEs include any Common Terminology Criteria of Adverse Events 4.0 while being treated with pegIFNα, irrespective of attribution. Nine patients (25%) experienced a total of the 12 SAEs listed above.

LFT, liver function tests (aspartate transaminase/alanine transaminase).

^*Clinical features consistent with acute GVHD.

^†Pulmonary SAEs include pneumonitis (acute respiratory distress syndrome) related to infection (n = 1) and acute hypoxemia (n = 1).

^‡Clinical features consistent with gouty arthritis.

^§Met criteria for DLT.