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. 2021 Dec 13;5(23):5420–5428. doi: 10.1182/bloodadvances.2021005507

Table 3.

Clinical characteristics of patients with SMNs in the TCCSG L04-16 cohort

TCCSG n Primary cancer subtype Primary risk Day-8 risk SMN subtype NUDT15 genotype*
404 BCP-ALL HR HR AML HT
105 BCP-ALL HR HR AML WT
014-008 BCP-ALL SR SR AML WT
0616084 BCP-ALL HR HR AML HT
0616086 BCP-ALL HR HR-SCT OS HT
568 BCP-ALL SR SR MDS WT

BCP-ALL, B-cell precursor ALL; HR, high risk; HR-SCT, high-risk stem cell transplantation; HT, heterozygous type; MDS, myelodysplastic syndrome; OS, osteosarcoma; SR, standard risk; WT, wild type.

*

HT indicates heterozygous for rs116855232.