Fig. 7.

Akt increases BMPR2 expression during starvation. A Immunoblot of starved A549 cells or starved then treated with insulin for 60 min. BMPR2 expression was normalized to Actin, n = 2. B Immunoblot of lung cancer cells in regular media with FCS treated with Akt inhibitor MK-2206 for 24 h. C Immunoblot of starved A549 cells or starved then treated with insulin for 60 min with and without the Akt inhibitor MK-2206. D Immunofluorescence imaging for BMPR2 at the cell surface of starved cancer cells treated with insulin for 60 min with and without MK-2206. E Mean fluorescence of 4 experiments of starved cells treated with insulin for 60 min with and without MK-2206