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. Author manuscript; available in PMC: 2022 Jul 15.
Published in final edited form as: J Affect Disord. 2022 Apr 21;309:201–210. doi: 10.1016/j.jad.2022.04.106

Fig. 5.

Fig. 5.

No effect of DIM or 1,4-DHNA on anxiety behaviors in stressed mice. Baseline behaviors were examined. Animals were re-tested after 3 weeks of receiving vehicle or ligand, just before UCMS began. Animals were re-tested again post-UCMS, after 9 weeks of receiving ligands. Data is presented as the difference between the re-test at week 3 and baseline (ΔWk 3) and the re-test at week 9 and baseline (ΔWk 9). (A) Time spent in the center zone of OFT; (B) time spent in the light zone of L/D apparatus; (C) number of buried marbles; (D) NIH latency to take the first lick; (E) NIH total consumption of milk; and (F) time spent in open arms of the EPM in seconds, number of entries to the open and closed arms, and total crosses in the middle. The ANOVA analyses for each test can be found in Supplementary Material.