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. 2022 May 27;71(21):703–708. doi: 10.15585/mmwr.mm7121a2

TABLE. Mean weekly seizure- or epilepsy-related emergency department visits and overall emergency department visits, by age and sex, and percentage change* — National Syndromic Surveillance Program, United States, April 1–December 29, 2019–2021.

Characteristic Mean weekly visits, no. (95% CI)§
% Change
2019 2020 2021 2019–2020 2020–2021
Seizure or epilepsy ED visits
Age group, yrs
0–9
2,759 (2,660–2,864)
1,553 (1,504–1,593)
2,528 (2,462–2,593)
−44
63
10–19
1,893 (1,846–1,940)
1,413 (1,356–1,469)
1,749 (1,710–1,786)
−25
24
20–39
7,102 (7,037–7,165)
6,143 (5,957–6,316)
6,579 (6,478–6,680)
−13
7
40–59
6,476 (6,412–6,539)
5,701 (5,548–5,838)
5,769 (5,678–5,860)
−12
1
60–69
2,588 (2,561–2,617)
2,423 (2,373–2,467)
2,495 (2,468–2,524)
−6
3
≥70
2,641 (2,604–2,679)
2,504(2,441–2,561)
2,583 (2,557–2,613)
−5
3
Sex
Female
11,422 (11,344–11,501)
9,327 (9,044–9,579)
10,373 (10,280–10,470)
−18
11
Male
12,128 (12,039–12,236)
10,462 (10,214–10,694)
11,387 (11,296–11,470)
−14
9
Total
23,588 (23,429–23,739)
19,824 (19,295–20,311)
21,800 (21,614–21,969)
−16
10
All-cause ED visits
Age group, yrs
0–9
162,711 (154,767–171,195)
71,131 (67,015–74,824)
142,868 (137,805–147,822)
−56
101
10–19
127,264 (123,781–130,677)
79,594 (74,870–84,171)
114,353 (111,036–117,884)
−37
44
20–39
416,652 (413,210–420,159)
336,598 (322,674–348,693)
401,671 (394,081–409,796)
−19
19
40–59
347,606 (344,299–350,816)
288,453 (278,532–297,426)
337,317 (331,750–342,781)
−17
17
60–69
157,694 (156,596–158,946)
135,574 (130,804–139,547)
161,899 (160,116–163,865)
−14
19
≥70
231,619 (230,000–233,699)
193,202 (185,523–199,808)
231,799 (229,713–233,852)
−17
20
Sex
Female
797,473 (791,101–804,433)
593,418 (568,244–615,384)
755,769 (745,392–766,769)
−26
27
Male
651,555 (646,948–656,594)
513,365 (494,989–530,303)
636,576 (627,504–646,651)
−21
24
Total 1,451,717 (1,441,285–1,463,581) 1,109,069 (1,067,564–1,148,844) 1,395,349 (1,374,389–1,415,093) −24 26

Abbreviation: ED = emergency department.

* The percentage change in visits between the surveillance and reference periods (2019 [reference] versus 2020 [surveillance] and 2020 [reference] versus 2021 [surveillance]) was calculated as (ED visits during surveillance period – ED visits during reference period)/ED visits during reference period x 100%.

The National Syndromic Surveillance Program receives anonymized medical record information from approximately 71% of nonfederal EDs nationwide. To reduce artifactual impact from changes in reporting patterns, analyses were restricted to facilities with more consistent reporting of more complete data (coefficient of variation ≤40 and average weekly informative discharge diagnosis ≥75% complete during 2019–2021).

§ CIs were constructed using the percentile bootstrap method using 1,000 replicate samples of the weekly counts. CIs were formed using the 2.5th and 97.5th percentiles of the bootstrap distributions.