Table 2.
Repeatability study of XN-31. Repeated measurements of malaria-infected red blood cells (MI-RBC) on inclusion and after storage of the blood sample (vacutainer) for 24 (H24), 48 (H48), and 72 (H72) hours. For each blood sample, one tube was stored at room temperature (20–25 °C,) and one was kept at 4 °C. The two tubes with different storage conditions were tested at 24, 48, and 72 h and the mean of triplicate measurements of the number of parasites/μL (MI-RBC) was recorded (grey line: room temperature; white line: 4 °C). Eight patients were included in this study, with initial parasitaemia ranging from 2.4 to 288.3 parasites/μL.
| Inclusion |
H24 |
H48 |
H72 |
|
|---|---|---|---|---|
| Mean MI-RBC (parasites/μL): Storage at room temperature |
||||
| Samples | Mean MI-RBC (parasites/μL): Storage at 4 °C | |||
| 1 | 2444 | 2482 | 2343 | 2441 |
| 2445 | 2368 | 2454 | 2467 | |
| 2 | 2438 | 2399 | 2377 | 2527 |
| 2429 | 2462 | 2525 | 2577 | |
| 3 | 2947 | 1884 | 1719 | 1693 |
| 3836 | 1912 | 2083 | 2186 | |
| 4 | 5496 | 6908 | 5313 | 8341 |
| 5712 | 5481 | 5561 | 5466 | |
| 5 | 5524 | 4348 | 4029 | 3939 |
| 5591 | 5028 | 14,655 | 3417 | |
| 6 | 10,767 | 10,660 | 10,702 | 10,840 |
| 10,726 | 10,663 | 10,692 | 10,898 | |
| 7 | 205,239 | 206,403 | 205,568 | 202,832 |
| 204,969 | 204,864 | 202,806 | 204,232 | |
| 8 | 282,352 | 281,880 | 280,875 | 278,894 |
| 282,352 | 278,069 | 279,877 | 280,325 | |