Table 1.
Basic characteristics of the study population across quintiles of SBP complexity
| Characteristics a | Overall |
Quintiles of SBP complexity |
|||||
|---|---|---|---|---|---|---|---|
| (n=1,835) | Q1 (n=367) | Q2 (n=367) | Q3 (n=367) | Q4 (n=367) | Q5 (n=367) | P value | |
| Age at baseline, years | 71.0 (6.4) | 70.7 (6.2) | 71.3 (6.3) | 71.4 (6.7) | 70.9 (6.5) | 70.6 (6.1) | 0.61 |
| Women, % | 62.5 | 58.0 | 63.2 | 68.1 | 59.9 | 63.2 | 0.38 |
| SBP (mmHg) | 144 (21) | 143 (21) | 146 (21) | 147 (21) | 143 (21) | 140 (19) | 0.001 |
| DBP (mmHg) | 76 (11) | 76 (11) | 77 (12) | 77 (11) | 77 (11) | 75 (10) | 0.09 |
| Total cholesterol, mg/dL | 5.9 (0.9) | 6.0 (0.9) | 5.9 (1.0) | 6.0 (1.0) | 5.9 (0.9) | 5.8 (0.9) | 0.07 |
| HDL cholesterol, mg/dL | 1.4 (0.4) | 1.5 (0.4) | 1.4 (0.4) | 1.4 (0.4) | 1.4 (0.4) | 1.4 (0.4) | 0.01 |
| APOE genotype, % | 0.93 | ||||||
| ε3/ε3 | 59.1 | 59.8 | 58.6 | 59.6 | 59.7 | 58.0 | - |
| ε2/ε2 or ε2/ε3 | 13.8 | 11.8 | 16.0 | 12.6 | 12.8 | 15.7 | - |
| ε2/ε4 or ε3/ε4 | 25.0 | 25.9 | 23.5 | 25.8 | 25.6 | 24.0 | - |
| ε4/ε4 | 2.1 | 2.5 | 1.9 | 1.9 | 1.9 | 2.2 | - |
| Education, % | 0.21 | ||||||
| Primary/intermediate | 89.3 | 86.5 | 89.6 | 91.0 | 89.5 | 89.8 | - |
| Higher education | 10.7 | 13.5 | 10.4 | 9.0 | 10.5 | 10.2 | - |
| Smoking status, % | 0.04 | ||||||
| Never | 34.4 | 33.0 | 40.1 | 36.4 | 30.6 | 31.7 | - |
| Past | 47.7 | 49.2 | 48.9 | 43.8 | 49.6 | 47.1 | - |
| Current | 17.9 | 17.9 | 11.0 | 19.7 | 19.8 | 21.2 | - |
| Weight status, % b | <0.001 | ||||||
| Normal weight | 34.2 | 45.4 | 36.6 | 27.9 | 31.2 | 29.8 | - |
| Overweight | 46.6 | 44.8 | 47.5 | 50.0 | 45.5 | 45.2 | - |
| Obese | 19.2 | 9.8 | 15.8 | 22.1 | 23.3 | 25.1 | - |
| History of Diabetes, % | 12.0 | 8.9 | 10.7 | 13.7 | 12.7 | 13.8 | 0.03 |
| History of Hypertension, % | 65.8 | 61.0 | 71.7 | 70.8 | 64.3 | 61.1 | 0.32 |
| Antihypertensive medication use, % | 31.2 | 27.7 | 29.8 | 32.7 | 31.8 | 33.9 | 0.06 |
Abbreviations: SBP=systolic blood pressure; DBP=diastolic blood pressure; HDL=high-density lipoproteins; APOE= Apolipoprotein E. Data are shown in the format of means (SD) or percentages.
a
Characteristics at baseline (i.e. the third examination between 1997 and 1999 when continuous BP measurements were taken).
b
Weight status was assessed by body mass index (BMI), with overweight defined as 25≤ BMI <30 kg/m2 and obesity defined as BMI ≥30 kg/m2.