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. 2022 Apr 25;2022:3846217. doi: 10.1155/2022/3846217

Figure 3.

Figure 3

HMOX1 (HO-1) expression was significantly upregulated in KIRC, and its low expression predicted a poor prognosis. (a) HMOX1 expression profile across all tumor samples and paired normal tissues based on TCGA and GTEx database. (b) The expression of HMOX1 was significantly upregulated in KIRC compared to normal tissue. (c) Expression levels of HO-1 in A498, OS-RC-2, and 786-O cells as determined by western blot analysis. (d) Low expression of HMOX1 in KIRC predicted a poor prognosis (not in KIRP and KICH) with statistically significant significance. The data in (c) are expressed as the mean ± SD. ∗P < 0.05 vs. the normal tissue group, #P < 0.05 vs. HK-2 group. TCGA: The Cancer Genome Atlas; GTEx: Genotype-Tissue Expression; KIRC: kidney renal clear cell carcinoma; KIRP: kidney renal papillary cell carcinoma; KICH: kidney chromophobe.