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. 2022 May 31;17(5):e0269261. doi: 10.1371/journal.pone.0269261

Fig 2. ssAAV2-STC-1-FLAG shows diffuse intraocular expression after intracameral injection.

Fig 2

Three-month-old C57BL/6J mice (n = 26) received a single intracameral injection of ssAAV2-STC-1-FLAG in one eye and ssAAV2-GFP in the fellow eye (1 μL, intracameral injection, 3x109 VGs). Diffuse ocular expression was seen following delivery of STC-1-FLAG or GFP with the AAV2 vector. Cells in the iridocorneal angle including ciliary body (CB), anterior segment including cornea (C), iris (I), and lens capsule (L), and the retina showed expression of GFP (red fluorochrome) and STC-1-FLAG (green fluorochrome) at day one post-injection with ssAAV2-GFP and ssAAV2-STC-1-FLAG. Similar results were seen 4 days post-injection.