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. 2022 May 31;17(5):e0269224. doi: 10.1371/journal.pone.0269224

Table 2. Outcome measures (primary and secondary).

Outcome measures (Median) Citicoline (n = 49) Placebo (n = 50) P-value OR with 95% CI
PRIMARY OUTCOME
Change in stroke volume from baseline to 6 weeks (cm 3 ) 4.22 2.63 0.483
SECONDARY OUTCOME
mRS 0–2 at 90 days 32 (65.3%) 31 (62%) 0.732 0.92 (0.40–2.05)
NIHSS 0–2 at 90 days 20 (40.8%) 20 (40%) 0.934 0.96 (0.39–2.40)
Barthel index > = 95 at 90 days 8 (16.3%) 10 (20%) 0.564 0.87 (0.22–2.98)
Mortality rate at 90 days 10.2 (5/49) 14 (7/50) 0.468