Table 3.
Outcome | Ceftolozane/Tazobactam (n = 47) |
Standard of Care (n = 50) |
P Value |
---|---|---|---|
Microbiologically documented infection | 13 (28) | 12 (24) | .68 |
Microbiological response at EOIV | .86 | ||
Persistence | 1/13 (8) | 1/12 (8) | |
Eradication | 11/13 (85) | 9/12 (75) | |
Presumed eradication | 0/13 (0) | 1/12 (8) | |
Indeterminate | 1/13 (8) | 1/12 (8) | |
Microbiological response at TOC | .64 | ||
Persistence | 0/13 (0) | 1/12 (8) | |
Eradication | 3/13 (23) | 2/12 (17) | |
Presumed eradication | 8/13 (62) | 9/12 (75) | |
Indeterminate | 2/13 (15) | 0/12 (0) | |
Microbiological response at LFU | .33 | ||
Persistence | 0/13 (0) | 1/12 (8) | |
Eradication | 2/13 (15) | 3/12 (25) | |
Presumed eradication | 81/3 (62) | 8/12 (67) | |
Indeterminate | 3/13 (23) | 0/12 (0) | |
Relapse | 0/12 (0) | 0/11 (0) |
Data are presented as No. of patients (%) unless otherwise indicated.
Abbreviations: EOIV, end of intravenous therapy; LFU, late follow-up; TOC, test of cure.