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. 2022 Feb 14;9(6):ofac079. doi: 10.1093/ofid/ofac079

Table 3.

Microbiological Outcome of Patients Who Received Ceftolozane/Tazobactam and Those Who Received the Standard of Care

Outcome Ceftolozane/Tazobactam
(n = 47)
Standard of Care
(n = 50)
P Value
Microbiologically documented infection 13 (28) 12 (24) .68
Microbiological response at EOIV .86
 Persistence 1/13 (8) 1/12 (8)
 Eradication 11/13 (85) 9/12 (75)
 Presumed eradication 0/13 (0) 1/12 (8)
 Indeterminate 1/13 (8) 1/12 (8)
Microbiological response at TOC .64
 Persistence 0/13 (0) 1/12 (8)
 Eradication 3/13 (23) 2/12 (17)
 Presumed eradication 8/13 (62) 9/12 (75)
 Indeterminate 2/13 (15) 0/12 (0)
Microbiological response at LFU .33
 Persistence 0/13 (0) 1/12 (8)
 Eradication 2/13 (15) 3/12 (25)
 Presumed eradication 81/3 (62) 8/12 (67)
 Indeterminate 3/13 (23) 0/12 (0)
 Relapse 0/12 (0) 0/11 (0)

Data are presented as No. of patients (%) unless otherwise indicated.

Abbreviations: EOIV, end of intravenous therapy; LFU, late follow-up; TOC, test of cure.