Table 3.
Functional outcomes | n | Baselinea | 120 days follow-upa | Difference | 95% CI | P-value |
---|---|---|---|---|---|---|
UWS FR, mL/minute | 10 | 0.13 ± 0.02 | 0.18 ± 0.02 | 0.06 | 0.03 to 0.09 | .0009 |
UWS FR, % change from baseline | 10 | 0 ± 12.4 | 50.2 ± 12.4 | 50.2 | 23.97 to 76.44 | .0005 |
SWS FR, mL/minute | 10 | 0.66 ± 0.11 | 0.75 ± 0.1 | 0.09 | 0.02 to 0.16 | .017 |
SWS FR, % change from baseline | 10 | 0 ± 6.5 | 20.2 ± 6.5 | 20.2 | 5.14 to 35.22 | .0099 |
XQ summary score (0-100) | 10 | 53.5 ± 6.7 | 30.9 ± 6.7 | −22.6 | −33.57 to −11.68 | .0004 |
EORTC QLQ-H&N35 (scores 0-100) | ||||||
HNDR | 10 | 73.3 ± 7.2 | 46.7 ± 7.2 | −26.7 | −46.93 to −6.41 | .013 |
HNSS | 10 | 46.7 ± 8.3 | 23.3 ± 8.3 | −23.3 | −41.52 to −5.15 | .015 |
HNSW | 10 | 26.7 ± 4.8 | 16.7 ± 4.8 | −10.0 | −17.87 to −2.12 | .016 |
Scintigraphic uptake score (scores 0-4) | ||||||
All glands | 10 | 1.7 ± 0.2 | 1.8 ± 0.2 | 0.1 | −0.06 to 0.16 | .34 |
PG | 10 | 2.3 ± 0.2 | 2.4 ± 0.2 | 0.1 | −0.06 to 0.16 | .34 |
SMG | 10 | 0.9 ± 0.2 | 0.9 ± 0.2 | −0.1 | −0.16 to 0.06 | .34 |
Scintigraphic excretion fraction, % | ||||||
All glands | 10 | 53.3 ± 4.8 | 55.3 ± 4.8 | 2.0 | −4.75 to 8.76 | .52 |
PG | 10 | 59.3 ± 6.0 | 60.8 ± 6.0 | 1.4 | −6.85 to 9.94 | .70 |
SMG | 10 | 40.3 ± 5.0 | 44.3 ± 5.0 | 4.0 | −4.16 to 12.06 | .28 |
Saliva composition, mmol/L | ||||||
UWS chloride | 8 | 21.7 ± 2.3 | 19.0 ± 2.4 | −2.68 | −7.46 to 2.09 | .23 |
SWS chloride | 9 | 26.5 ± 3.4 | 25.9 ± 3.4 | −0.61 | −3.41 to 2.18 | .63 |
UWS phosphate | 8 | 4.7 ± 0.4 | 4.4 ± 0.4 | −0.28 | −1.44 to 0.88 | .55 |
SWS phosphate | 9 | 3.8 ± 0.2 | 3.6 ± 0.2 | −0.22 | −0.88 to 0.44 | .47 |
UWS potassium | 8 | 19.1 ± 1.4 | 18.2 ± 1.6 | −0.91 | −4.57 to 2.74 | .54 |
SWS potassium | 9 | 19.4 ± 1.1 | 19.4 ± 1.2 | 0.02 | −2.85 to 2.81 | .99 |
UWS sodium | 8 | 8.4 ± 1.4 | 7.2 ± 1.5 | −1.17 | −3.80 to 1.46 | .32 |
SWS sodium | 9 | 14.7 ± 3.3 | 15.7 ± 3.4 | 1.02 | −3.57 to 5.62 | .62 |
Values are least squares means and standard errors, unless otherwise stated.