Table 2.

Topological analysis of core targets in ‘lupenone -target-disease’ network.

Gene name	Betweenness centrality	Closeness centrality	Degree
INS	0.068121	0.756757	95
TP53	0.02875	0.679612	74
TNF	0.023754	0.669856	71
SRC	0.022054	0.660377	68
ESR1	0.013141	0.633484	59
JUN	0.009126	0.625	56
PTGS2	0.008946	0.611354	51
HSP90AA1	0.01071	0.608696	50
CTNNB1	0.009412	0.606061	49
MTOR	0.008296	0.606061	49
AR	0.007686	0.598291	46
MAPK14	0.005711	0.595745	45
IL10	0.006232	0.59322	44
SIRT1	0.005683	0.59322	44
PIK3CA	0.005147	0.588235	42
IL4	0.005161	0.585774	41
KIT	0.004878	0.585774	41
RELA	0.003582	0.585774	41
HIF1A	0.004726	0.583333	40
EDN1	0.004736	0.578512	38
PIK3R1	0.004544	0.578512	38
MDM2	0.004322	0.578512	38
AGT	0.006154	0.576132	37
CRP	0.005963	0.576132	37